Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

R. Ferguson, Lynnette; Chen, Helen; Collins, Andrew; Connell, Marisa; Damia, Giovanna; Dasgupta, Santanu; Malhotra, Meenakshi; K. Meeker, Alan; Amedei, Amedeo; Amin, Amr; M. Ashraf, S.; Aquilano, Katia; S. Azmi, Asfar; Bhakta-Guha, Dipita; Bilsland, Alan; S. Boosani, Chandra; Chen, Sophie; Rosa Ciriolo, Maria; Fujii, Hiromasa; Guha, Gunjan; Halicka, Dorota; G. Helferich, William; Nicol Keith, W.; I. Mohammed, Sulma; Niccolai, Elena; Yang, Xujuan; Honoki, Kanya; R. Parslow, Virginia; Prakash, Satya; Rezazadeh, Sarallah; E. Shackelford, Rodney; Sidransky, David; T. Tran, Phuoc; S. Yang, Eddy; A. Maxwell, Christopher

doi:10.1016/j.semcancer.2015.03.005

Public

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

Published in Seminars in Cancer Biology • Apr 11, 2015

Authors:

Lynnette R. Ferguson

Helen Chen

Andrew Collins

Abstract

Genomic instability can initiate cancer, augment progression, and influence the overall prognosis of the affected patient. Genomic instability arises from many different pathways, such as telomere damage, centrosome amplification, epigenetic modifications, and DNA damage from endogenous and exogenou...

Subject

Genome instability

Biology

DNA damage

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