A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

H. Duerr, Richard; D. Taylor, Kent; R. Brant, Steven; D. Rioux, John; S. Silverberg, Mark; J. Daly, Mark; Hillary Steinhart, A.; Abraham, Clara; Regueiro, Miguel; M. Griffiths, Anne; Dassopoulos, Themistocles; Bitton, Alain; Yang, Huiying; R. Targan, Stephan; W. Datta, Lisa; O. Kistner, Emily; Philip Schumm, L.; T. Lee, Annette; K. Gregersen, Peter; Michael Barmada, M.; I. Rotter, Jerome; L. Nicolae, Dan; H. Cho, Judy

doi:10.1126/science.1135245

Public

A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

Published in Science • Oct 26, 2006

Authors:

Richard H. Duerr

Kent D. Taylor

Steven R. Brant

Abstract

The inflammatory bowel diseases Crohn's disease and ulcerative colitis are common, chronic disorders that cause abdominal pain, diarrhea, and gastrointestinal bleeding. To identify genetic factors that might contribute to these disorders, we performed a genome-wide association study. We found a high...

Subject

Inflammatory bowel disease

Disease

Genome-wide association study

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