Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials

Branford, Susan; Fletcher, Linda; C.P. Cross, Nicholas; Müller, Martin; Hochhaus, Andreas; Kim, Dong‐Wook; P. Radich, Jerald; Saglio, Giuseppe; Pane, Fabrizio; Kamel‐Reid, Suzanne; Lynn Wang, Y.; D. Press, Richard; Lynch, Kevin; Rudzki, Zbigniew; M. Goldman, John; P. Hughes, Timothy

doi:10.1182/blood-2008-04-150680

Public

Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials

Published in Blood • Aug 7, 2008

Authors:

Susan Branford

Linda Fletcher

Nicholas C.P. Cross

Abstract

An international basis for comparison of BCR-ABL mRNA levels is required for the common interpretation of data derived from individual laboratories. This will aid clinical decisions for individual patients with chronic myeloid leukemia (CML) and assist interpretation of results from clinical studies...

Subject

Concordance

Statistics

Clinical trial

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