The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas.

N, Burnichon; V, Rohmer; L, Amar; P, Herman; S, Leboulleux; V, Darrouzet; P, Niccoli; D, Gaillard; G, Chabrier; F, Chabolle; I, Coupier; P, Thieblot; P, Lecomte; J, Bertherat; N, Wion-Barbot; A, Murat; A, Venisse; PF, Plouin; X, Jeunemaitre; AP, Gimenez-Roqueplo

doi:10.1210/jc.2008-2504

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The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas.

Shared by NobleBlocks on May 19, 2009 • 12:00 AM UTC

Authors:

Burnichon N

Rohmer V

Amar L

Abstract

Context Germline mutations in SDHx genes cause hereditary paraganglioma.Objective The aim of the study was to assess the indications for succinate dehydrogenase (SDH) genetic testing in a prospective study.Design A total of 445 patients with head and neck and/or thoracic-abdominal or pelvic paragang...

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