COBRA combination therapy in patients with early rheumatoid arthritis: Long‐term structural benefits of a brief intervention

Landewé, Robert; Boers, Maarten; C. Verhoeven, Arco; Westhovens, René; A F J van de Laar, Mart; M. Markusse, H.; Christiaan van Denderen, J.; Louise Westedt, Marie; J. Peeters, André; A. C. Dijkmans, Ben; Jacobs, Piet; Boonen, Annelies; van der Heijde, Désirée; van der Linden, Sjef

doi:10.1002/art.10083

Public

COBRA combination therapy in patients with early rheumatoid arthritis: Long‐term structural benefits of a brief intervention

Published in Arthritis & Rheumatism • Feb 1, 2002

Authors:

Robert Landewé

Maarten Boers

Arco C. Verhoeven

Abstract

OBJECTIVE: The Combinatietherapie Bij Reumatoide Artritis (COBRA) trial demonstrated that step-down combination therapy with prednisolone, methotrexate, and sulfasalazine (SSZ) was superior to SSZ monotherapy for suppressing disease activity and radiologic progression of rheumatoid arthritis (RA). T...

Subject

Cobra

Medicine

Rheumatoid arthritis

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