Light-Harvesting Ionic Dendrimer Porphyrins as New Photosensitizers for Photodynamic Therapy

Nishiyama, Nobuhiro; R. Stapert, Hendrik; Zhang, Guodong; Takasu, Daisuke; Jiang, Donglin; Nagano, Tetsuo; Aida, Takuzo; Kataoka, Kazunori

doi:10.1021/bc025597h

Public

Light-Harvesting Ionic Dendrimer Porphyrins as New Photosensitizers for Photodynamic Therapy

Published in Bioconjugate Chemistry • Dec 19, 2002

Authors:

Nobuhiro Nishiyama

Hendrik R. Stapert

Guodong Zhang

Abstract

Photodynamic therapy (PDT) is a promising therapeutic modality for treatment of solid tumors. In this study, third-generation aryl ether dendrimer porphyrins (DPs) with either 32 quaternary ammonium groups (32(+)DPZn) or 32 carboxylic groups (32(-)DPZn) were evaluated as a novel, supramolecular clas...

Subject

Chemistry

Dendrimer

Photodynamic therapy

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