Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone

Ohnishi, Makoto; Golparian, Daniel; Shimuta, Ken; Saika, Takeshi; Hoshina, Shinji; Iwasaku, Kazuhiro; Nakayama, Shu‐ichi; Kitawaki, Jo; Unemo, Magnus

doi:10.1128/aac.00325-11

Public

Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone

Published in Antimicrobial Agents and Chemotherapy • May 17, 2011

Authors:

Makoto Ohnishi

Daniel Golparian

Ken Shimuta

Abstract

Recently, the first Neisseria gonorrhoeae strain (H041) that is highly resistant to the extended-spectrum cephalosporin (ESC) ceftriaxone, the last remaining option for empirical first-line treatment, was isolated. We performed a detailed characterization of H041, phenotypically and genetically, to ...

Subject

Neisseria gonorrhoeae

Gonorrhea

Ceftriaxone

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