Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell Carcinoma

Chiou, Shih-Hwa; Yu, Cheng-Chia; Huang, Chi-Yang; Lin, Shu-Chun; Liu, Chung-Ji; Tsai, Tung-Hu; Chou, Shiu-Huey; Chien, Chian-Shiu; Ku, Hung-Hai; Lo, Jeng-Fan

doi:10.1158/1078-0432.ccr-07-4404

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Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell Carcinoma

Shared by NobleBlocks on Jul 1, 2008 • 12:00 AM UTC

Authors:

Shih-Hwa Chiou

Cheng-Chia Yu

Chi-Yang Huang

Abstract

Abstract Purpose: Oral squamous cell carcinoma (OSCC), like many solid tumors, contains a heterogeneous population of cancer cells. Recent data suggest that a rare subpopulation of cancer cells, termed cancer stem cells (CSC), is capable of initiating, maintaining, and expanding the growth of tumor....

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