Platelet lysates promote mesenchymal stem cell expansion: A safety substitute for animal serum in cell-based therapy applications

Doucet, Christelle; Ernou, Isabelle; Zhang, Yizhou; Llense, Jean-Roch; Bégot, Laurent; Holy, Xavier; Lataillade, Jean‐Jacques

doi:10.1002/jcp.20391

Public

Platelet lysates promote mesenchymal stem cell expansion: A safety substitute for animal serum in cell-based therapy applications

Published in Journal of Cellular Physiology • Jan 1, 2005

Authors:

Christelle Doucet

Isabelle Ernou

Yizhou Zhang

Abstract

Mesenchymal stem cells (MSCs) are considered as emergent "universal" cells and various tissue repair programs using MSCs are in development. In vitro expansion of MSCs is conventionally achieved in medium containing fetal calf serum (FCS) and is increased by addition of growth factors. However, for ...

Subject

Mesenchymal stem cell

Subculture (biology)

Basic fibroblast growth factor

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