Helicobacter pylori infection potentiates the inhibition of gastric acid secretion by omeprazole

Gillen, Derek; A Wirz, A; D Neithercut, W; Ardill, J.; E McColl, K

doi:10.1136/gut.44.4.468

Public

Helicobacter pylori infection potentiates the inhibition of gastric acid secretion by omeprazole

Published in Gut • Apr 1, 1999

Authors:

Derek Gillen

A A Wirz

W D Neithercut

Abstract

BACKGROUND: Omeprazole has a greater intragastric pH elevating effect in Helicobacter pylori positive than negative subjects. Ammonia production by H pylori has been suggested as a probable mechanism. AIMS: To assess the effect of H pylori status on gastric acid secretion during omeprazole treatment...

Subject

Omeprazole

Helicobacter pylori

Gastric acid

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