Disclosure of APOE Genotype for Risk of Alzheimer's Disease

C. Green, Robert; Scott Roberts, J.; Adrienne Cupples, L.; Relkin, Norman; J. Whitehouse, Peter; Brown, Tamsen; LaRusse Eckert, Susan; Barber Butson, Melissa; Dessa Sadovnick, A.; A. Quaid, Kimberly; Chen, Clara; Cook‐Deegan, Robert; A. Farrer, Lindsay

doi:10.1056/nejmoa0809578

Public

Disclosure of APOE Genotype for Risk of Alzheimer's Disease

Published in New England Journal of Medicine • Jul 15, 2009

Authors:

Robert C. Green

J. Scott Roberts

L. Adrienne Cupples

Abstract

BACKGROUND: The apolipoprotein E (APOE) genotype provides information on the risk of Alzheimer's disease, but the genotyping of patients and their family members has been discouraged. We examined the effect of genotype disclosure in a prospective, randomized, controlled trial. METHODS: We randomly a...

Subject

Medicine

Depression (economics)

Anxiety

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