A Phase II Study of Gemcitabine and 5-Fluorouracil in Metastatic Pancreatic Cancer: An Eastern Cooperative Oncology Group Study (E3296)

Berlin, Jordan; Adak, Sudeshna; J. Vaughn, David; Flinker, David; S. Blaszkowsky, Lawrence; E. Harris, Jules; B. Benson, Al

doi:10.1159/000012103

Public

A Phase II Study of Gemcitabine and 5-Fluorouracil in Metastatic Pancreatic Cancer: An Eastern Cooperative Oncology Group Study (E3296)

Published in Oncology • Jan 1, 2000

Authors:

Jordan Berlin

Sudeshna Adak

David J. Vaughn

Abstract

Gemcitabine has recently been compared favorably to 5-fluorouracil (5-FU) as the standard chemotherapy for advanced pancreas cancer. Based on phase I data that combining gemcitabine with 5-FU is safe and has evidence for clinical activity, a phase II trial was conducted by the Eastern Cooperative On...

Subject

Gemcitabine

Medicine

Internal medicine

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