IL-1 alpha (-889) promoter polymorphism is a risk factor for osteomyelitis.

V, Asensi; V, Alvarez; E, Valle; A, Meana; J, Fierer; E, Coto; JA, Carton; JA, Maradona; J, Paz; MA, Dieguez; la Fuente B, de; A, Moreno; S, Rubio; MJ, Tuya; J, Sarasúa; S, Llames; JM, Arribas

doi:10.1002/ajmg.a.20137

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IL-1 alpha (-889) promoter polymorphism is a risk factor for osteomyelitis.

Shared by NobleBlocks on Jun 1, 2003 • 12:00 AM UTC

Authors:

Asensi V

Alvarez V

Valle E

Abstract

As osteomyelitis (OM) induces the synthesis of inflammatory cytokines and IL-1 mediates bone resorption by osteoclasts we determined if there is an association between certain common polymorphisms of the genes encoding proinflammatory cytokines (IL-1 alpha and beta, IL-6, TNF-alpha) and OM in adults...

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