Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population.

N, Aoyama; N, Takahashi; S, Saito; N, Maeno; R, Ishihara; X, Ji; H, Miura; M, Ikeda; T, Suzuki; T, Kitajima; Y, Yamanouchi; Y, Kinoshita; K, Yoshida; N, Iwata; T, Inada; N, Ozaki

doi:10.1111/j.1601-183x.2006.00231.x

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Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population.

Shared by NobleBlocks on Jun 1, 2006 • 12:00 AM UTC

Authors:

Aoyama N

Takahashi N

Saito S

Abstract

Several lines of evidence suggest that metabolic changes in the kynurenic acid (KYNA) pathway are related to the etiology of schizophrenia. The inhibitor of kynurenine 3-monooxygenase (KMO) is known to increase KYNA levels, and the KMO gene is located in the chromosome region associated with schizop...

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