Association study between kynurenine 3‐monooxygenase gene and schizophrenia in the Japanese population

Aoyama, N.; Takahashi, Nagahide; Saito, Susumu; Maeno, N.; Ishihara, Rei; Ji, Xiaohui; Miura, Hideki; Ikeda, Masashi; Сузуки, Т.; Kitajima, Tsuyoshi; Yamanouchi, Yoshio; Kinoshita, Yoko; Yoshida, Ken; Iwata, N.; Inada, Toshiya; Ozaki, Norio

doi:10.1111/j.1601-183x.2006.00231.x

Public

Association study between kynurenine 3‐monooxygenase gene and schizophrenia in the Japanese population

Published in Genes Brain & Behavior • Apr 27, 2006

Authors:

N. Aoyama

Nagahide Takahashi

Susumu Saito

Abstract

Several lines of evidence suggest that metabolic changes in the kynurenic acid (KYNA) pathway are related to the etiology of schizophrenia. The inhibitor of kynurenine 3-monooxygenase (KMO) is known to increase KYNA levels, and the KMO gene is located in the chromosome region associated with schizop...

Subject

Haplotype

Single-nucleotide polymorphism

Kynurenic acid

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