Intracellular mGluR5 Can Mediate Synaptic Plasticity in the Hippocampus

A. Purgert, Carolyn; Izumi, Yukitoshi; I. Jong, Yuh‐Jiin; Kumar, Vikas; F. Zorumski, Charles; L. O’Malley, Karen

doi:10.1523/jneurosci.3451-13.2014

Public

Intracellular mGluR5 Can Mediate Synaptic Plasticity in the Hippocampus

Published in Journal of Neuroscience • Mar 26, 2014

Authors:

Carolyn A. Purgert

Yukitoshi Izumi

Yuh‐Jiin I. Jong

Abstract

Metabotropic glutamate receptor 5 (mGluR5) is widely expressed throughout the CNS and participates in regulating neuronal function and synaptic transmission. Recent work in the striatum led to the groundbreaking discovery that intracellular mGluR5 activation drives unique signaling pathways, includi...

Subject

Metabotropic glutamate receptor 5

Metabotropic glutamate receptor

Intracellular

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