Effects of Exenatide (Exendin-4) on Glycemic Control and Weight Over 30 Weeks in Metformin-Treated Patients With Type 2 Diabetes

A. DeFronzo, Ralph; E. Ratner, Robert; Han, Jenny; Dong Hwan Kim, Dennis; Fineman, Mark; Baron, Alain

doi:10.2337/diacare.28.5.1092

Public

Effects of Exenatide (Exendin-4) on Glycemic Control and Weight Over 30 Weeks in Metformin-Treated Patients With Type 2 Diabetes

Published in Diabetes Care • May 1, 2005

Authors:

Ralph A. DeFronzo

Robert E. Ratner

Jenny Han

Abstract

OBJECTIVE: This study evaluates the ability of the incretin mimetic exenatide (exendin-4) to improve glycemic control in patients with type 2 diabetes failing to achieve glycemic control with maximally effective metformin doses. RESEARCH DESIGN AND METHODS: A triple-blind, placebo-controlled, 30-wee...

Subject

Exenatide

Medicine

Metformin

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