Grape-seed procyanidins act as antiinflammatory agents in endotoxin-stimulated RAW 264.7 macrophages by inhibiting NFkB signaling pathway.

Ximena, Terra,; Josep, Valls,; Xavier, Vitrac,; Jean-Michel, Mérrillon,; Lluís, Arola,; Anna, Ardèvol,; Cinta, Bladé,; Juan, Fernandez-Larrea,; Gerard, Pujadas,; Josepa, Salvadó,; Mayte, Blay,

doi:10.1021/jf0633185

Public

Grape-seed procyanidins act as antiinflammatory agents in endotoxin-stimulated RAW 264.7 macrophages by inhibiting NFkB signaling pathway.

Published in Journal of agricultural and food chemistry • May 30, 2007

Authors:

Terra, Ximena

Valls, Josep

Vitrac, Xavier

Abstract

Procyanindin extract (PE) is a mixture of polyphenols, mainly procyanidins, obtained from grape seed with putative antiinflammatory activity. We evaluated the PE effect on RAW 264.7 macrophages stimulated with lipopolysaccharide plus interferon-gamma that show a rapid enhanced production of prostagl...

Subject

Animals

Anti-Inflammatory Agents

Grape Seed Extract

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