Paired immunoglobulin-like receptor B regulates platelet activation

Fan, Xuemei; Shi, Panlai; Dai, Jing; Lu, Yeling; Chen, Xue; Liu, Xiaoye; Zhang, Kandi; Wu, Xiaolin; Sun, Yueping; Wang, Kemin; Zhu, Li; Cheng Zhang, Cheng; Zhang, Junfeng; Chen, Guoqiang; Zheng, Junke; Liu, Junling

doi:10.1182/blood-2014-03-557645

Public

Paired immunoglobulin-like receptor B regulates platelet activation

Published in Blood • Jul 29, 2014

Authors:

Xuemei Fan

Panlai Shi

Jing Dai

Abstract

Murine paired immunoglobulin-like receptors B (PIRB), as the ortholog of human leukocyte immunoglobulin-like receptor B2 (LILRB2), is involved in a variety of biological functions. Here, we found that PIRB and LILRB2 were expressed in mouse and human platelets, respectively. PIRB intracellular domai...

Subject

Platelet

GPVI

Platelet activation

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