Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer

A. Rosenberg, Steven; T. Lotze, Michael; Muul, Linda; F. Leitman, Susan; E. Chang, Alfred; E. Ettinghausen, Stephen; L. Matory, Yvedt; M. Skibber, John; Shiloni, Eitan; T. Vetto, John; A. Seipp, Claudia; Simpson, Colleen; M. Reichert, Cheryl

doi:10.1056/nejm198512053132327

Public

Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer

Published in New England Journal of Medicine • Dec 5, 1985

Authors:

Steven A. Rosenberg

Michael T. Lotze

Linda Muul

Abstract

We describe here the preliminary results of the systemic administration of autologous lymphokine-activated killer (LAK) cells and the recombinant-derived lymphokine interleukin-2 to patients with advanced cancer. This regimen was based on animal models in which the systemic administration of LAK cel...

Subject

Medicine

Lymphokine-activated killer cell

Lymphokine

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