Prophylactic thyroidectomy in 75 children and adolescents with hereditary medullary thyroid carcinoma: German and Austrian experience.

H, Dralle; O, Gimm; D, Simon; K, Frank-Raue; G, Görtz; B, Niederle; RA, Wahl; B, Koch; S, Walgenbach; R, Hampel; MM, Ritter; F, Spelsberg; A, Heiss; R, Hinze; W, Höppner

doi:10.1007/s002689900463

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Prophylactic thyroidectomy in 75 children and adolescents with hereditary medullary thyroid carcinoma: German and Austrian experience.

Shared by NobleBlocks on Jul 1, 1998 • 12:00 AM UTC

Authors:

Dralle H

Gimm O

Simon D

Abstract

When mutations of the RETproto-oncogene were found in 1993 to account for hereditary medullary thyroid carcinoma (MTC), surgeons obtained the opportunity to operate on patients prophylactically (i. e., at a clinically asymptomatic stage). Whether this approach is justified, and, if so, when and to w...

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