Prophylactic Thyroidectomy in 75 Children and Adolescents with Hereditary Medullary Thyroid Carcinoma: German and Austrian Experience

Dralle, Henning; Gimm, Oliver; Simon, Dietmar; Frank‐Raue, Karin; Görtz, G.; Niederle, Bruno; A. Wahl, Robert; Koch, Bernd; Walgenbach, Siegfried; Hampel, Rainer; M. Ritter, Michael; Spelsberg, F.; Heiss, Agnes; Hinze, Raoul; Höppner, Wolfgang

doi:10.1007/s002689900463

Public

Prophylactic Thyroidectomy in 75 Children and Adolescents with Hereditary Medullary Thyroid Carcinoma: German and Austrian Experience

Published in World Journal of Surgery • Jul 1, 1998

Authors:

Henning Dralle

Oliver Gimm

Dietmar Simon

Abstract

When mutations of the RETproto-oncogene were found in 1993 to account for hereditary medullary thyroid carcinoma (MTC), surgeons obtained the opportunity to operate on patients prophylactically (i. e., at a clinically asymptomatic stage). Whether this approach is justified, and, if so, when and to w...

Subject

Medicine

Hypoparathyroidism

Asymptomatic

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