Serum HER‐2/<i>neu</i> and relative resistance to trastuzumab‐based therapy in patients with metastatic breast cancer

M. Ali, Suhail; P. Carney, Walter; J. Esteva, Francisco; Fornier, Monica; N. Harris, Lyndsay; J. Köstler, Wolfgang; Lotz, Jean‐Pierre; Lüftner, Diana; Pichon, M.F.; Lipton, Allan

doi:10.1002/cncr.23689

Public

Serum HER‐2/neu and relative resistance to trastuzumab‐based therapy in patients with metastatic breast cancer

Published in Cancer • Jul 25, 2008

Authors:

Suhail M. Ali

Walter P. Carney

Francisco J. Esteva

Abstract

BACKGROUND: Previous reports based on small patient numbers suggested that changes in serum HER-2/neu levels may predict response or lack of response to trastuzumab-based therapies in metastatic breast cancer (MBC). The objectives of this study were to pool data from 307 patients with MBC from 7 med...

Subject

Medicine

Trastuzumab

Metastatic breast cancer

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