Lipopolysaccharide fever is initiated <i>via</i> a capsaicin‐sensitive mechanism independent of the subtype‐1 vanilloid receptor

Doğan, M.Devrim; Patel, Shreya; Y. Rudaya, Alla; A. Steiner, Alexandre; Székely, Miklós; A. Romanovsky, Andrej

doi:10.1038/sj.bjp.0705977

Public

Lipopolysaccharide fever is initiated via a capsaicin‐sensitive mechanism independent of the subtype‐1 vanilloid receptor

Published in British Journal of Pharmacology • Dec 1, 2004

Authors:

M.Devrim Doğan

Shreya Patel

Alla Y. Rudaya

Abstract

As pretreatment with intraperitoneal capsaicin (8-methyl-N-vanillyl-6-nonenamide, CAP), an agonist of the vanilloid receptor known as VR1 or transient receptor potential channel-vanilloid receptor subtype 1 (TRPV-1), has been shown to block the first phase of lipopolysaccharide (LPS) fever in rats, ...

Subject

TRPV

Capsazepine

Resiniferatoxin

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