Anti-tumor effect of rutin on human neuroblastoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis.

Hongyan, Chen,; Qing, Miao,; Miao, Geng,; Jing, Liu,; Yazhuo, Hu,; Lei, Tian,; Jingkun, Pan,; Yi, Yang,

doi:10.1155/2013/269165

Public

Anti-tumor effect of rutin on human neuroblastoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis.

Published in TheScientificWorldJournal • Jan 1, 2013

Authors:

Chen, Hongyan

Miao, Qing

Geng, Miao

Abstract

AIMS: To further investigate the antineuroblastoma effect of rutin which is a type of flavonoid. METHODS: The antiproliferation of rutin in human neuroblastoma cells LAN-5 were detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Chemotaxis of LAN-5 cells was assesse...

Subject

Apoptosis

Cell Line

Tumor

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