Pharmacokinetics of gabapentin in subjects with various degrees of renal function

A. Blum, Robert; J. Comstock, Thomas; A. Sica, Domenic; W. Schultz, Robert; Keller, Erich; Reetze, P.; N. Bockbrader, Howard; Tuerck, Deitrich; A. Busch, Janice; A. Reece, Phillip; J. Sedman, Allen

doi:10.1038/clpt.1994.118

Public

Pharmacokinetics of gabapentin in subjects with various degrees of renal function

Published in Clinical Pharmacology & Therapeutics • Aug 1, 1994

Authors:

Robert A. Blum

Thomas J. Comstock

Domenic A. Sica

Abstract

The pharmacokinetics of oral gabapentin (400 mg) was studied in normal subjects and in subjects with various degrees of renal function. Sixty subjects participated in this three-center study. None of the subjects were receiving hemodialysis. Plasma and urine samples were collected for up to 264 hour...

Subject

Gabapentin

Pharmacokinetics

Renal function

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