Pharmacokinetics of gabapentin in subjects with various degrees of renal function.

A Blum, R; J Comstock, T; A Sica, D; W Schultz, R; Keller, E; Reetze, P; Bockbrader, H; Tuerck, D; A Busch, J; A Reece, P

doi:10.1038/clpt.1994.118

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Pharmacokinetics of gabapentin in subjects with various degrees of renal function.

Shared by NobleBlocks on Aug 1, 1994 • 12:00 AM UTC

Authors:

R A Blum

T J Comstock

D A Sica

Abstract

The pharmacokinetics of oral gabapentin (400 mg) was studied in normal subjects and in subjects with various degrees of renal function. Sixty subjects participated in this three-center study. None of the subjects were receiving hemodialysis. Plasma and urine samples were collected for up to 264 hour...

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