Interleukin-1 mediates thermal injury-induced lung damage through C-Jun NH2-terminal kinase signaling*

OBJECTIVE: The molecular mechanisms of lung damage following thermal injury are not clear. The purpose of this study was to determine whether interleukin (IL)-1 mediates burn-induced inducible nitric oxide synthase (iNOS) expression, peroxynitrite production, and lung damage through c-Jun NH2-termin... View More