The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide.

JA, Wedzicha; PM, Calverley; TA, Seemungal; G, Hagan; Z, Ansari; RA, Stockley

doi:10.1164/rccm.200707-973oc

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The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide.

Shared by NobleBlocks on Oct 4, 2007 • 12:00 AM UTC

Authors:

Wedzicha JA

Calverley PM

Seemungal TA

Abstract

Rationale Exacerbations are key drivers of morbidity and mortality in chronic obstructive pulmonary disease (COPD).Objectives We compared the relative efficacy of the long-acting inhaled bronchodilator/antiinflammatory combination (salmeterol/fluticasone propionate) 50/500 microg twice daily and the...

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