Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.

BACKGROUND Preconditioning (5 minutes of ischemia followed by 10 minutes of recovery) renders the heart very resistant to infarction from subsequent ischemia. This study tests whether adenosine receptors might mediate preconditioning protection. METHODS AND RESULTS We examined the effect on infarct ... View More