The Anorexigenic Neuropeptide, Nesfatin-1, Is Indispensable for Normal Puberty Onset in the Female Rat

García-Galiano, David; M. Navarro, Víctor; Roa, Juan; Ruíz-Pino, Francisco; A. Sánchez-Garrido, Miguel; Pineda, Rafael; M. Castellano, Juan; T. Martı́n-Romero, Marı́a; Aguilar, E.; Gaytán, Francisco; Diéguez, Carlos; Pinilla, Lucía; Tena‐Sempere, Manuel

doi:10.1523/jneurosci.5828-09.2010

Public

The Anorexigenic Neuropeptide, Nesfatin-1, Is Indispensable for Normal Puberty Onset in the Female Rat

Published in Journal of Neuroscience • Jun 9, 2010

Authors:

David García-Galiano

Víctor M. Navarro

Juan Roa

Abstract

The hypothalamic peptide, nesfatin-1, derived from the precursor NEFA/nucleobindin 2 (NUCB2), was recently identified as anorexigenic signal, acting in a leptin-independent manner. Yet its participation in the regulation of other biological functions gated by body energy status remains unexplored. W...

Subject

Internal medicine

Endocrinology

Hypothalamus

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