Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid‐refractory, grade III – IV acute graft‐versus‐host disease

M. Ball, Lynne; Ester Bernardo, Maria; Roelofs, Helene; J. D. van Tol, Maarten; Contoli, Benedetta; Jan Zwaginga, Jaap; Antonietta Avanzini, Maria; Conforti, Antonella; Bertaina, Alice; Giorgiani, Giovanna; M. Jol‐van der Zijde, Cornelia; Zecca, Marco; Le Blanc, Katarina; Frassoni, Francesco; Maarten Egeler, R.; E. Fibbe, Willem; C. Lankester, Arjan; Locatelli, Franco

doi:10.1111/bjh.12545

Public

Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid‐refractory, grade III – IV acute graft‐versus‐host disease

Published in British Journal of Haematology • Aug 31, 2013

Authors:

Lynne M. Ball

Maria Ester Bernardo

Helene Roelofs

Abstract

Mesenchymal stromal cell (MSC) infusions have been reported to be effective in patients with steroid-refractory, acute graft-versus-host disease (aGvHD) but comprehensive data on paediatric patients are limited. We retrospectively analysed a cohort of 37 children (aged 3 months-17 years) treated wit...

Subject

Medicine

Refractory (planetary science)

Steroid

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