Phase II study of imatinib in advanced chordoma.

S, Stacchiotti; A, Longhi; V, Ferraresi; G, Grignani; A, Comandone; R, Stupp; A, Bertuzzi; E, Tamborini; S, Pilotti; A, Messina; C, Spreafico; A, Gronchi; P, Amore; V, Vinaccia; PG, Casali

doi:10.1200/jco.2011.35.3656

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Phase II study of imatinib in advanced chordoma.

Shared by NobleBlocks on Feb 13, 2012 • 12:00 AM UTC

Authors:

Stacchiotti S

Longhi A

Ferraresi V

Abstract

Purpose To explore the antitumor activity of imatinib in patients with advanced platelet-derived growth factor β (PDGFB)/PDGF receptor β (PDGFRB)-positive chordomas.Patients and methods In a collaborative Italian-Swiss, prospective, phase II clinical study conducted from November 2004 through April ...

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