Distinct Sets of Genetic Alterations in Melanoma

A. Curtin, John; Fridlyand, Jane; Kageshita, Toshiro; Patel, Hetal; J. Busam, Klaus; Kutzner, Heinz; Cho, Kwang‐Hyun; Aiba, Setsuya; Bröcker, Eva‐Bettina; E. LeBoit, Philip; Pinkel, Dan; C. Bastian, Boris

doi:10.1056/nejmoa050092

Public

Distinct Sets of Genetic Alterations in Melanoma

Published in New England Journal of Medicine • Nov 16, 2005

Authors:

John A. Curtin

Jane Fridlyand

Toshiro Kageshita

Abstract

BACKGROUND: Exposure to ultraviolet light is a major causative factor in melanoma, although the relationship between risk and exposure is complex. We hypothesized that the clinical heterogeneity is explained by genetically distinct types of melanoma with different susceptibility to ultraviolet light...

Subject

Melanoma

Medicine

Ultraviolet light

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