Posaconazole vs. Fluconazole or Itraconazole Prophylaxis in Patients with Neutropenia

A. Cornely, Oliver; Maertens, Johan; J. Winston, Drew; R. Perfect, John; J. Ullmann, Andrew; J. Walsh, Thomas; Helfgott, David; Hołowiecki, Jerzy; Stockelberg, Dick; Goh, Yeow-Tee; Petrini, Mario; Hardalo, Cathy; Suresh, Ramachandran; Angulo-González, D.

doi:10.1056/nejmoa061094

Public

Posaconazole vs. Fluconazole or Itraconazole Prophylaxis in Patients with Neutropenia

Published in New England Journal of Medicine • Jan 25, 2007

Authors:

Oliver A. Cornely

Johan Maertens

Drew J. Winston

Abstract

BACKGROUND: Patients with neutropenia resulting from chemotherapy for acute myelogenous leukemia or the myelodysplastic syndrome are at high risk for difficult-to-treat and often fatal invasive fungal infections. METHODS: In this randomized, multicenter study involving evaluators who were unaware of...

Subject

Posaconazole

Itraconazole

Medicine

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