Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers.

Background We previously conducted gene expression microarray analyses to identify novel indicators for colorectal cancer (CRC) metastasis and prognosis from which we identified PVT-1 as a candidate gene. PVT-1, which encodes a long noncoding RNA, mapped to chromosome 8q24 whose copy-number amplific... View More