Randomized, Placebo-Controlled Trial of Combined Pentoxifylline and Tocopherol for Regression of Superficial Radiation-Induced Fibrosis

Delanian, S.; Porcher, Raphaël; Balla-Mekias, Saı̈da; Lefaix, Jean-Louis

doi:10.1200/jco.2003.06.064

Public

Randomized, Placebo-Controlled Trial of Combined Pentoxifylline and Tocopherol for Regression of Superficial Radiation-Induced Fibrosis

Published in Journal of Clinical Oncology • Jun 30, 2003

Authors:

S. Delanian

Raphaël Porcher

Saı̈da Balla-Mekias

Abstract

PURPOSE: Radiation-induced fibrosis (RIF) is a rare morbid complication of radiotherapy, without an established method of management. RIF treatment with a combination of pentoxifylline (PTX) and alpha-tocopherol (vitamin E; Vit E) was recently prompted by the good results of a clinical trial and an ...

Subject

Medicine

Placebo

Pentoxifylline

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