A Moderate and Transient Deficiency of Maternal Thyroid Function at the Beginning of Fetal Neocorticogenesis Alters Neuronal Migration

Ausó, Eva; Lavado-Autric, Rosalía; Cuevas‐Romero, Estela; Escobar del Rey, Francisco; Morreale de Escobar, Gabriella; Berbel, Pere

doi:10.1210/en.2004-0274

Public

A Moderate and Transient Deficiency of Maternal Thyroid Function at the Beginning of Fetal Neocorticogenesis Alters Neuronal Migration

Published in Endocrinology • Apr 20, 2004

Authors:

Eva Ausó

Rosalía Lavado-Autric

Estela Cuevas‐Romero

Abstract

Epidemiological studies and case reports show that even a relatively minor degree of maternal hypothyroxinemia during the first half of gestation is potentially dangerous for optimal fetal neurodevelopment. Our experimental approach was designed to result in a mild and transient period of maternal h...

Subject

Corticogenesis

Internal medicine

Endocrinology

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