Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

, DIAGRAM; S. Kooner, Jaspal; , MuTHER; Saleheen, Danish; Sim, Xueling; Sehmi, Joban; Zhang, Weihua; Frossard, Philippe; Been, Latonya; Chia, Kee‐Seng; S. Dimas, Antigone; Hassanali, Neelam; Jafar, Tazeen; B. M. Jowett, Jeremy; Li, Man; Radha, Venkatesan; D. Rees, Simon; Takeuchi, Fumihiko; Young, Robin; Aung, Tin; Basit, Abdul; Chidambaram, Manickam; Das, Debashish; Grundberg, Elin; K. Hedman, Åsa; Zafar Iqbal Hydrie, Muhammad; Islam, Muhammed; Chuen Khor, Chiea; Kowlessur, Sudhir; M. Kristensen, Malene; Liju, Samuel; Lim, Wei‐Yen; R Matthews, David; Liu, Jianjun; P. Morris, Andrew; C. Nica, Alexandra; Pinidiyapathirage, Janani; Prokopenko, Inga; Rasheed, Asif; Samuel, Maria; Shah, Nabi; Samad Shera, A.; S. Small, Kerrin; Suo, Chen; R. Wickremasinghe, Ananda; Yin Wong, Tien; Yang, Ming‐Yu; Zhang, Fan; R. Abecasis, Gonçalo; Barnett, Anthony; J. Caulfield, Mark; Deloukas, Panos; M. Frayling, Timothy; Froguel, Philippe; Kato, Norihiro; Katulanda, Prasad; A. Kelly, M.; Liang, Junbin; Mohan, Viswanathan; K. Sanghera, Dharambir; Scott, James; Seielstad, Mark; Zimmet, Paul; Elliott, Paul; Ying Teo, Yik; I. McCarthy, Mark; Danesh, John; Shyong Tai, E; C. Chambers, John

doi:10.1038/ng.921

Public

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

Published in Nature Genetics • Aug 28, 2011

Authors:

DIAGRAM

Jaspal S. Kooner

MuTHER

Abstract

We carried out a genome-wide association study of type-2 diabetes (T2D) in individuals of South Asian ancestry. Our discovery set included 5,561 individuals with T2D (cases) and 14,458 controls drawn from studies in London, Pakistan and Singapore. We identified 20 independent SNPs associated with T2...

Subject

Type 2 diabetes

Biology

Single-nucleotide polymorphism

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