Elevated plasma sVCAM‐1 levels in children with sickle cell disease: Impact of chronic transfusion therapy

Sakhalkar, Vishwas; P. Rao, Sreedhar; Weedon, Jeremy; T. Miller, Scott

doi:10.1002/ajh.20016

Public

Elevated plasma sVCAM‐1 levels in children with sickle cell disease: Impact of chronic transfusion therapy

Published in American Journal of Hematology • Apr 22, 2004

Authors:

Vishwas Sakhalkar

Sreedhar P. Rao

Jeremy Weedon

Abstract

Vascular cell adhesion molecule-1 (VCAM-1) has been implicated as being important in the pathophysiology of acute pain episodes (APE) and acute chest syndrome (ACS) of sickle cell disease (SCD). The frequency of these episodes is reduced by chronic transfusion therapy. The impact of chronic transfus...

Subject

Medicine

Asymptomatic

Acute chest syndrome

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