Inhibitory effects of an anti-IgE antibody E25 on allergen-induced early asthmatic response.

P Boulet, L; R Chapman, K; Côté, J; Kalra, S; Bhagat, R; A Swystun, V; Laviolette, M; D Cleland, L; Deschesnes, F; Q Su, J; DeVault, A; B Fick, R; W Cockcroft, D

doi:10.1164/ajrccm.155.6.9196083

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Inhibitory effects of an anti-IgE antibody E25 on allergen-induced early asthmatic response.

Shared by NobleBlocks on Jun 1, 1997 • 12:00 AM UTC

Authors:

L P Boulet

K R Chapman

J Côté

Abstract

Inhaled allergens, acting through IgE-dependent mechanisms, are important triggers of asthma symptoms and inducers of airway hyperresponsiveness and airway inflammation. The effect of anti-IgE recombinant humanized monoclonal antibody-E25 (rhuMAb-E25) on the provocation concentration of allergen cau...

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