Long non-coding RNA MALAT1 promotes tumour growth and metastasis in colorectal cancer through binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex

Ji, Qing; Zhang, Ling‐Yue; Liu, X.; Zhou, Lihong; Wang, W; Han, Ziduan; Sui, Hua; Tang, Yufei; WANG, YIXUAN; Liu, N; Ren, Jingyuan; Hou, Fenggang; Li, Qi

doi:10.1038/bjc.2014.383

Public

Long non-coding RNA MALAT1 promotes tumour growth and metastasis in colorectal cancer through binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex

Published in British Journal of Cancer • Jul 15, 2014

Authors:

Qing Ji

Ling‐Yue Zhang

X. Liu

Abstract

BACKGROUND: Metastasis associated with lung adenocarcinoma transcript-1 (MALAT1) is a functional long non-coding RNA (lncRNA), which is highly expressed in several tumours, including colorectal cancer (CRC). Its biological function and mechanism in the prognosis of human CRC is still largely under i...

Subject

MALAT1

Polypyrimidine tract-binding protein

Cancer research

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