Universal Real-Time PCR for the Detection and Quantification of Adeno-Associated Virus Serotype 2-Derived Inverted Terminal Repeat Sequences

Aurnhammer, Christine; Haase, Maren; Muether, Nadine; A Hausl, Martin; Rauschhuber, Christina; Huber, Ingrid; Nitschko, Hans; Busch, Ulrich; Sing, Andreas; Ehrhardt, Anja; Baiker, Armin

doi:10.1089/hgtb.2011.034

Public

Universal Real-Time PCR for the Detection and Quantification of Adeno-Associated Virus Serotype 2-Derived Inverted Terminal Repeat Sequences

Published in Human Gene Therapy Methods • Feb 1, 2012

Authors:

Christine Aurnhammer

Maren Haase

Nadine Muether

Abstract

Viral vectors based on various naturally occurring adeno-associated virus (AAV) serotypes are among the most promising tools in human gene therapy. For the production of recombinant AAV (rAAV) vectors, researchers are focusing predominantly on cross-packaging an artificial AAV genome based on seroty...

Subject

Adeno-associated virus

Biology

Genome

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