Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

Katoh, Yasutake; Itoh, Ken; Yoshida, Eisaku; Miyagishi, Makoto; Fukamizu, Akiyoshi; Yamamoto, Masayuki

doi:10.1046/j.1365-2443.2001.00469.x

Public

Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

Published in Genes to Cells • Oct 1, 2001

Authors:

Yasutake Katoh

Ken Itoh

Eisaku Yoshida

Abstract

BACKGROUND: Nrf2 belongs to the Cap-N-Collar (CNC) transcription factor family and is essential for the antioxidant responsive element (ARE)-mediated expression of a group of detoxifying and antioxidant genes. The forced expression of Nrf2 in mammalian cells activates the expression of target genes ...

Subject

Transactivation

CREB

Transcription factor

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