Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study

C. Gouw, Samantha; G. van der Bom, Johanna; Auerswald, Günter; Escuriola Ettinghausen, Carmen; Tedgård, Ulf; Marijke van den Berg, H.

doi:10.1182/blood-2006-11-056317

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Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study

Published in Blood • Jan 12, 2007

Authors:

Samantha C. Gouw

Johanna G. van der Bom

Günter Auerswald

Abstract

It has been suggested that plasma-derived factor VIII products induce fewer inhibitors than recombinant factor VIII products. We investigated the relationship of factor VIII product type and switching between factor VIII products with the risk to develop inhibitors. This multicenter retrospective co...

Subject

Risk factor

Medicine

Von Willebrand factor

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