Apolipoprotein E gene polymorphism and colorectal cancer: gender-specific modulation of risk and prognosis

A. Watson, Mark; J. Gay, Laura; Stebbings, William; Speakman, Chris; Bingham, Sheila; Loktionov, Alexandre

doi:10.1042/cs20020329

Public

Apolipoprotein E gene polymorphism and colorectal cancer: gender-specific modulation of risk and prognosis

Published in Clinical Science • May 1, 2003

Authors:

Mark A. Watson

Laura J. Gay

William Stebbings

Abstract

Apolipoprotein E ( ApoE ) gene polymorphism is a major factor in lipid metabolism. It has been suggested that this polymorphism can modulate colorectal tumour risk. We tested this hypothesis for colorectal cancer (CRC). ApoE genotype was determined in 206 patients with CRC and 353 healthy controls f...

Subject

Genotype

Odds ratio

Internal medicine

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