RIG-I, MDA5 and TLR3 Synergistically Play an Important Role in Restriction of Dengue Virus Infection

Nasirudeen, A.M.A.; Hui Wong, Hui; Thien, Peiling; Xu, Shengli; Lam, Kong‐Peng; Xiang Liu, Ding

doi:10.1371/journal.pntd.0000926

Public

RIG-I, MDA5 and TLR3 Synergistically Play an Important Role in Restriction of Dengue Virus Infection

Published in PLoS neglected tropical diseases • Jan 4, 2011

Authors:

A.M.A. Nasirudeen

Hui Hui Wong

Peiling Thien

Abstract

Dengue virus (DV) infection is one of the most common mosquito-borne viral diseases in the world. The innate immune system is important for the early detection of virus and for mounting a cascade of defense measures which include the production of type 1 interferon (IFN). Hence, a thorough understan...

Subject

MDA5

Biology

Innate immune system

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