Microbiota‐dependent metabolite trimethylamine‐N‐oxide is associated with disease severity and survival of patients with chronic heart failure

Trøseid, Marius; Ueland, Thor; R. Hov, Johannes; Svardal, Asbjørn; Gregersen, Ida; P. Dahl, C.; Aakhus, Svend; Gude, E.; Bjørndal, Bodil; Halvorsen, Bente; H. Karlsen, Tom; Aukrust, Pål; Gullestad, Lars; K. Berge, Rolf; Yndestad, Arne

doi:10.1111/joim.12328

Public

Microbiota‐dependent metabolite trimethylamine‐N‐oxide is associated with disease severity and survival of patients with chronic heart failure

Published in Journal of Internal Medicine • Nov 8, 2014

Authors:

Marius Trøseid

Thor Ueland

Johannes R. Hov

Abstract

OBJECTIVES: Recent metabolomic, experimental and clinical studies have demonstrated that trimethylamine-N-oxide (TMAO), a microbiota-dependent metabolite from dietary phosphatidylcholine and carnitine, is a strong predictor of coronary artery disease (CAD). This finding suggests a link between the g...

Subject

Trimethylamine N-oxide

Medicine

Internal medicine

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