Resetting the Biological Clock: Mediation of Nocturnal Circadian Shifts by Glutamate and NO

Ding, Jian; Dong, Chen; Todd Weber, E.; E. Faiman, Lia; A. Rea, Michael; U. Gillette, Martha

doi:10.1126/science.7527589

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Resetting the Biological Clock: Mediation of Nocturnal Circadian Shifts by Glutamate and NO

Published in Science • Dec 9, 1994

Authors:

Jian Ding

Chen Dong

E. Todd Weber

Abstract

Circadian rhythms of mammals are timed by an endogenous clock with a period of about 24 hours located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Light synchronizes this clock to the external environment by daily adjustments in the phase of the circadian oscillation. The mechanism has ...

Subject

Circadian rhythm

Suprachiasmatic nucleus

Glutamate receptor

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