The Philippine cynomolgus monkey (Macaca fasicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease

P Walsh, G; V. Tan, Esterlina; Canteiro Cruz, Eduardo; M. Abalos, Rodolfo; G. Villahermosa, Laarni; J. Young, Leon; V. Cellona, Roland; B. Narareno, Jerome; A. Horwitz, Marcus

doi:10.1038/nm0496-430

Public

The Philippine cynomolgus monkey (Macaca fasicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease

Published in Nature Medicine • Apr 1, 1996

Authors:

G P Walsh

Esterlina V. Tan

Eduardo Canteiro Cruz

Abstract

A nonhuman primate model of tuberculosis that closely resembles human disease is urgently needed. We have evaluated the Philippine cynomolgus monkey, Macaca fasicularis, as a model of TB. Cynomolgus monkeys challenged intratracheally with extremely high doses of Mycobacterium tuberculosis (10(5) or ...

Subject

Subclinical infection

Nonhuman primate

Tuberculosis

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!