Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin, and primidone.

DB, Smith; RH, Mattson; JA, Cramer; JF, Collins; RA, Novelly; B, Craft

doi:10.1111/j.1528-1157.1987.tb05778.x

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Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin, and primidone.

Shared by NobleBlocks on Jan 1, 1987 • 12:00 AM UTC

Authors:

Smith DB

Mattson RH

Cramer JA

Abstract

In 1985 a 5-year multicenter Veterans Administration Cooperative Study was completed that compared the efficacy and toxicity of phenobarbital, carbamazepine, phenytoin, and primidone in a double-blind prospective study design. A total of 622 patients, either previously untreated or undertreated, wer...

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