High-dose recombinant endotoxin neutralizing protein improves survival in rabbits, with Escherichia coli sepsis.

RA, Saladino; AM, Stack; C, Thompson; F, Sattler; TJ, Novitsky; GR, Siber; GR, Fleisher

doi:10.1097/00003246-199607000-00023

Public

High-dose recombinant endotoxin neutralizing protein improves survival in rabbits, with Escherichia coli sepsis.

Shared by NobleBlocks on Jul 1, 1996 • 12:00 AM UTC

Authors:

Saladino RA

Stack AM

Thompson C

Abstract

Objective To assess the benefit of a recombinant endotoxin neutralizing protein from Limulus polyphemus in treating Gram-negative bacterial sepsis in rabbits.Design Prospective, blinded, controlled, laboratory trial.Setting Animal research laboratory.Subjects New Zealand White rabbits.Interventions ...

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