Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis

M. Black, Dennis; D. Delmas, Pierre; Eastell, Richard; R. Reid, Ian; Boonen, Steven; A. Cauley, Jane; Cosman, Felicia; Lakatos, Péter; Leung, Ping‐Chung; Man, Z.; Mautalén, C.; Mesenbrink, Peter; Hu, Huilin; Caminis, John; Tong, Karen; Rosario-Jansen, Theresa; Krasnow, Joel; F. Hue, Trisha; E. Sellmeyer, Deborah; Fink Eriksen, Erik; R. Cummings, Steven

doi:10.1056/nejmoa067312

Public

Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis

Published in New England Journal of Medicine • May 3, 2007

Authors:

Dennis M. Black

Pierre D. Delmas

Richard Eastell

Abstract

BACKGROUND: A single infusion of intravenous zoledronic acid decreases bone turnover and improves bone density at 12 months in postmenopausal women with osteoporosis. We assessed the effects of annual infusions of zoledronic acid on fracture risk during a 3-year period. METHODS: In this double-blind...

Subject

Zoledronic acid

Medicine

Osteoporosis

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